[HTML][HTML] Challenges in metabolomics-based tests, biomarkers revealed by metabolomic analysis, and the promise of the application of metabolomics in precision …

A Di Minno, M Gelzo, M Caterino, M Costanzo… - International Journal of …, 2022 - mdpi.com
… to be used in precision medicine and precision prevention approaches. The use of big
biobanks and electronic medical records that integrate biological information with clinical data …

[HTML][HTML] CHDH, a key mitochondrial enzyme, plays a diagnostic role in metabolic disorders diseases and tumor progression

Y Li, X Shen, X Yang, F Lian, Y Li, J Li, Y Huang… - Frontiers in …, 2023 - frontiersin.org
… In recent years, the role of CHDH in medicine has … the difficulties in purifying CHDH,
biochemists lost interest in the enzyme and little is known about the biochemical properties of human

Understanding choline bioavailability and utilization: first step toward personalizing choline nutrition

YQ Goh, G Cheam, Y Wang - Journal of Agricultural and Food …, 2021 - ACS Publications
… for many age-related health problems, there is a pressing need to … via mitochondrial enzyme
choline dehydrogenase, (60) and … , citicoline is a medicine containing CDP-choline that was …

The glycine betaine role in neurodegenerative, cardiovascular, hepatic, and renal diseases: Insights into disease and dysfunction networks

JA Rosas-Rodríguez, EM Valenzuela-Soto - Life sciences, 2021 - Elsevier
… , agriculture, and clinical medical studies due to its chemical and … synthesis: the choline
dehydrogenase and betaine aldehyde … with the progression of health problems, most of the GB …

Osmotic Contribution of Synthesized Betaine by Choline Dehydrogenase Using In Vivo and In Vitro Models of Post-traumatic Syringomyelia

DD Pukale, D Lazarenko, SR Aryal, F Khabaz… - Cellular and Molecular …, 2023 - Springer
… and its synthesis enzyme choline dehydrogenase (CHDH) … known osmoprotectant role
in biological systems, along with … options to overcome challenges associated with clinical …

Recent advances in ionic liquids in biomedicine

AM Curreri, S Mitragotri, EEL Tanner - Advanced Science, 2021 - Wiley Online Library
… Ionic liquids have shown great promise in navigating biological … is extremely important to
the field of medicine. Ishikawa et al. [ … challenges when the detection is based on a biological

Choline oxidases

G Gadda - The Enzymes, 2020 - Elsevier
… The enzyme is important both for medical and … is an obligatory and thermodynamically
challenging step in the reaction of … A biochemical characterization of a choline oxidase from a …

[HTML][HTML] Microfluidic sensors based on two-dimensional materials for chemical and biological assessments

S Radhakrishnan, M Mathew, CS Rout - Materials Advances, 2022 - pubs.rsc.org
… technology that shows promise in health care and … health care and environmental applications
including wearable sensors are critically addressed in this review. Finally, the challenges

The promise of the gut microbiome as part of individualized treatment strategies

DA Schupack, RAT Mars, DH Voelker… - Nature reviews …, 2022 - nature.com
challenge in medicine. … human studies are included and we do not account for differences
in the level of confidence in the findings based on association alone or additional biological

[HTML][HTML] Molecular imaging of brain tumors and drug delivery using CEST MRI: promises and challenges

J Huang, Z Chen, SW Park, JHC Lai, KWY Chan - Pharmaceutics, 2022 - mdpi.com
promises of CEST MRI in the identification of tumors, tumor grading, detecting molecular
alterations related to isocitrate dehydrogenase … which was validated by biochemical means [93]. …